Mateina
Brand names,
Mateina
Analogs
Mateina
Brand Names Mixture
Mateina
Chemical_Formula
C8H10N4O2
Mateina
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Mateina
fda sheet
Mateina
msds (material safety sheet)
Mateina
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Mateina
Molecular Weight
194.191 g/mol
Mateina
Melting Point
238 oC
Mateina
H2O Solubility
22 mg/ml
Mateina
State
Solid
Mateina
LogP
-0.07
Mateina
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Mateina
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Mateina
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Mateina
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Mateina
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Mateina
Patient Information
Mateina
Organisms Affected
Humans and other mammals