Dexitac
Brand names,
Dexitac
Analogs
Dexitac
Brand Names Mixture
Dexitac
Chemical_Formula
C8H10N4O2
Dexitac
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Dexitac
fda sheet
Dexitac
msds (material safety sheet)
Dexitac
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Dexitac
Molecular Weight
194.191 g/mol
Dexitac
Melting Point
238 oC
Dexitac
H2O Solubility
22 mg/ml
Dexitac
State
Solid
Dexitac
LogP
-0.07
Dexitac
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Dexitac
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Dexitac
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Dexitac
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Dexitac
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Dexitac
Patient Information
Dexitac
Organisms Affected
Humans and other mammals