Caffine
Brand names,
Caffine
Analogs
Caffine
Brand Names Mixture
Caffine
Chemical_Formula
C8H10N4O2
Caffine
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Caffine
fda sheet
Caffine
msds (material safety sheet)
Caffine
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Caffine
Molecular Weight
194.191 g/mol
Caffine
Melting Point
238 oC
Caffine
H2O Solubility
22 mg/ml
Caffine
State
Solid
Caffine
LogP
-0.07
Caffine
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Caffine
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Caffine
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Caffine
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Caffine
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Caffine
Patient Information
Caffine
Organisms Affected
Humans and other mammals