Darvon Compound-65
Brand names,
Darvon Compound-65
Analogs
Darvon Compound-65
Brand Names Mixture
Darvon Compound-65
Chemical_Formula
C8H10N4O2
Darvon Compound-65
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Darvon Compound-65
fda sheet
Darvon Compound-65
msds (material safety sheet)
Darvon Compound-65
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Darvon Compound-65
Molecular Weight
194.191 g/mol
Darvon Compound-65
Melting Point
238 oC
Darvon Compound-65
H2O Solubility
22 mg/ml
Darvon Compound-65
State
Solid
Darvon Compound-65
LogP
-0.07
Darvon Compound-65
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Darvon Compound-65
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Darvon Compound-65
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Darvon Compound-65
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Darvon Compound-65
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Darvon Compound-65
Patient Information
Darvon Compound-65
Organisms Affected
Humans and other mammals