Darvon Compound
Brand names,
Darvon Compound
Analogs
Darvon Compound
Brand Names Mixture
Darvon Compound
Chemical_Formula
C8H10N4O2
Darvon Compound
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Darvon Compound
fda sheet
Darvon Compound
msds (material safety sheet)
Darvon Compound
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Darvon Compound
Molecular Weight
194.191 g/mol
Darvon Compound
Melting Point
238 oC
Darvon Compound
H2O Solubility
22 mg/ml
Darvon Compound
State
Solid
Darvon Compound
LogP
-0.07
Darvon Compound
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Darvon Compound
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Darvon Compound
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Darvon Compound
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Darvon Compound
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Darvon Compound
Patient Information
Darvon Compound
Organisms Affected
Humans and other mammals