Theobromine ME
Brand names,
Theobromine ME
Analogs
Theobromine ME
Brand Names Mixture
Theobromine ME
Chemical_Formula
C8H10N4O2
Theobromine ME
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
Theobromine ME
fda sheet
Theobromine ME
msds (material safety sheet)
Theobromine ME
Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Theobromine ME
Molecular Weight
194.191 g/mol
Theobromine ME
Melting Point
238 oC
Theobromine ME
H2O Solubility
22 mg/ml
Theobromine ME
State
Solid
Theobromine ME
LogP
-0.07
Theobromine ME
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
Theobromine ME
Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Theobromine ME
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Theobromine ME
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Theobromine ME
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
Theobromine ME
Patient Information
Theobromine ME
Organisms Affected
Humans and other mammals