Stim
Brand names,
Stim
Analogs
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Brand Names Mixture
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Chemical_Formula
C24H40N8O4
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RX_link
http://www.rxlist.com/cgi/generic2/dipyrid.htm
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
F. G. Fischer, et al., and U.S. Pat. 3,031,450 (1962)
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Molecular Weight
504.626 g/mol
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Melting Point
163oC
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H2O Solubility
Slightly
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State
Solid
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LogP
-0.01
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Dosage Forms
Tablets
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Indication
For as an adjunct to coumarin anticoagulants in the prevention of postoperative thromboembolic complications of cardiac valve replacement and also used in prevention of angina.
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Pharmacology
Dipyridamole, a non-nitrate coronary vasodilator that also inhibits platelet aggregation, is combined with other anticoagulant drugs, such as warfarin, to prevent thrombosis in patients with valvular or vascular disorders. Dipyridamole is also used in myocardial perfusion imaging, as an antiplatelet agent, and in combination with aspirin for stroke prophylaxis.
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Absorption
70%
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side effects and Toxicity
Hypotension, if it occurs, is likely to be of short duration, but a vasopressor drug may be used if necessary. The oral LD50 in rats is greater than 6,000 mg/kg while in the dogs, the oral LD50 is approximately 400 mg/kg. LD50=8.4g/kg (orally in rat)
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Patient Information
Description
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This medicine is sometimes called a "blood thinner". This medicine prevents blood clots form forming and may be given following a stroke or heart attack or for patient who have an irregular heart beat.
General Information
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This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider.
Proper use of this medicine
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Take this medicine exactly as directed. Do not take more or less of this medicine than prescribed. Your doctor may change the dosage of this medicine. Keep all lab appointments.
Missed Dose
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Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
Storage
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Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed.
Possible Side Effects
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Check with your doctor as soon as possible if you experience any of the following:
nosebleeds
excessive bleeding from cuts
bleeding from your gums
excessive bruising
discoloration of urine or stools
black tarry stools.
If you experience any of these side effects, talk to you health care provider as soon as possible, back or stomach pain, black tarry stools, blood in urine, coughing up blood, difficulty breathing, dizziness or fainting spells, heavy menstrual bleeding, n
Stim
Organisms Affected
Humans and other mammals