Stimul
Brand names,
Stimul
Analogs
Stimul
Brand Names Mixture
Stimul
Chemical_Formula
C8H10N4O2
Stimul
RX_link
http://www.rxlist.com/cgi/generic3/caffeine.htm
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fda sheet
Stimul
msds (material safety sheet)
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Synthesis Reference
U.S. Pat. 2,508,545 (1950)
Stimul
Molecular Weight
194.191 g/mol
Stimul
Melting Point
238 oC
Stimul
H2O Solubility
22 mg/ml
Stimul
State
Solid
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LogP
-0.07
Stimul
Dosage Forms
Capsule; Drops; Liquid; Pill; Tablet
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Indication
For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.
Stimul
Pharmacology
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain.
Stimul
Absorption
Readily absorbed after oral or parenteral administration. The peak plasma level for caffeine range from 6-10mg/L and the mean time to reach peak concentration ranged from 30 minutes to 2 hours.
Stimul
side effects and Toxicity
LD50=127 mg/kg (orally in mice)
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Patient Information
Stimul
Organisms Affected
Humans and other mammals