Reclomide
Brand names,
Reclomide
Analogs
Reclomide
Brand Names Mixture
Reclomide
Chemical_Formula
C14H22ClN3O2
Reclomide
RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Reclomide
fda sheet
Reclomide
msds (material safety sheet)
Reclomide
Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Reclomide
Molecular Weight
299.796 g/mol
Reclomide
Melting Point
147.25 oC
Reclomide
H2O Solubility
200 mg/L
Reclomide
State
Solid
Reclomide
LogP
2.464
Reclomide
Dosage Forms
Liquid; Syrup; Tablet
Reclomide
Indication
For the treatment of gastroesophageal reflux disease (GERD)
Reclomide
Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Reclomide
Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Reclomide
side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Reclomide
Patient Information
Reclomide
Organisms Affected
Humans and other mammals