Metochlopramide en es it fr

Metochlopramide Brand names, Metochlopramide Analogs

Metochlopramide Brand Names Mixture

  • No information avaliable

Metochlopramide Chemical_Formula

C14H22ClN3O2

Metochlopramide RX_link

http://www.rxlist.com/cgi/generic2/metoclo.htm

Metochlopramide fda sheet

Metochlopramide FDA

Metochlopramide msds (material safety sheet)

Metochlopramide MSDS

Metochlopramide Synthesis Reference

Thominet, U.S. Pat. 3,177,252 (1965)

Metochlopramide Molecular Weight

299.796 g/mol

Metochlopramide Melting Point

147.25 oC

Metochlopramide H2O Solubility

200 mg/L

Metochlopramide State

Solid

Metochlopramide LogP

2.464

Metochlopramide Dosage Forms

Liquid; Syrup; Tablet

Metochlopramide Indication

For the treatment of gastroesophageal reflux disease (GERD)

Metochlopramide Pharmacology

Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.

Metochlopramide Absorption

Rapidly and well absorbed (oral bioavailability 80±15.5%).

Metochlopramide side effects and Toxicity

Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.

Metochlopramide Patient Information

Metochlopramide Organisms Affected

Humans and other mammals