Neu-Sensamide
Brand names,
Neu-Sensamide
Analogs
Neu-Sensamide
Brand Names Mixture
Neu-Sensamide
Chemical_Formula
C14H22ClN3O2
Neu-Sensamide
RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Neu-Sensamide
fda sheet
Neu-Sensamide
msds (material safety sheet)
Neu-Sensamide
Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Neu-Sensamide
Molecular Weight
299.796 g/mol
Neu-Sensamide
Melting Point
147.25 oC
Neu-Sensamide
H2O Solubility
200 mg/L
Neu-Sensamide
State
Solid
Neu-Sensamide
LogP
2.464
Neu-Sensamide
Dosage Forms
Liquid; Syrup; Tablet
Neu-Sensamide
Indication
For the treatment of gastroesophageal reflux disease (GERD)
Neu-Sensamide
Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Neu-Sensamide
Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Neu-Sensamide
side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Neu-Sensamide
Patient Information
Neu-Sensamide
Organisms Affected
Humans and other mammals