Methochlopramide
Methochlopramide Brand names, Methochlopramide Analogs
- Apo-Metoclop
- Cerucal
- Clopra
- Clopra-Yellow
- Clopromate
- DEL
- Duraclamid
- Elieten
- Emetid
- Emperal
- Eucil
- Gastrese
- Gastro-Timelets
- Gastrobid
- Gastromax
- Gastronerton
- Gastrosil
- Gastrotablinen
- Gastrotem
- Imperan
- Maxeran
- Maxolon
- Meclopran
- Metaclopramide
- Metaclopromide
- Metamide
- Methochlopramide
- Methoclopramide
- Metochlopramide
- Metoclol
- Metoclopramida [Inn-Spanish]
- Metoclopramide Hcl
- Metoclopramide Hydrochloride
- Metoclopramide Intensol
- Metoclopramide Omega
- Metoclopramidum [Inn-Latin]
- Metocobil
- Metramid
- Moriperan
- Mygdalon
- Neu-Sensamide
- Nu-Metoclopramide
- Octamide
- Parmid
- Paspertin
- Peraprin
- Plasil
- Pms-Metoclopramide
- Pramiel
- Pramin
- Primperan
- Reclomide
- Reglan
- Reliveran
- Terperan
Methochlopramide Brand Names Mixture
- No information avaliable
Methochlopramide Chemical_Formula
C14H22ClN3O2
Methochlopramide RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Methochlopramide fda sheet
Methochlopramide msds (material safety sheet)
Methochlopramide Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Methochlopramide Molecular Weight
299.796 g/mol
Methochlopramide Melting Point
147.25 oC
Methochlopramide H2O Solubility
200 mg/L
Methochlopramide State
Solid
Methochlopramide LogP
2.464
Methochlopramide Dosage Forms
Liquid; Syrup; Tablet
Methochlopramide Indication
For the treatment of gastroesophageal reflux disease (GERD)
Methochlopramide Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Methochlopramide Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Methochlopramide side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Methochlopramide Patient Information
Methochlopramide Organisms Affected
Humans and other mammals
