Maxolon
Brand names,
Maxolon
Analogs
Maxolon
Brand Names Mixture
Maxolon
Chemical_Formula
C14H22ClN3O2
Maxolon
RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Maxolon
fda sheet
Maxolon
msds (material safety sheet)
Maxolon
Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Maxolon
Molecular Weight
299.796 g/mol
Maxolon
Melting Point
147.25 oC
Maxolon
H2O Solubility
200 mg/L
Maxolon
State
Solid
Maxolon
LogP
2.464
Maxolon
Dosage Forms
Liquid; Syrup; Tablet
Maxolon
Indication
For the treatment of gastroesophageal reflux disease (GERD)
Maxolon
Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Maxolon
Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Maxolon
side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Maxolon
Patient Information
Maxolon
Organisms Affected
Humans and other mammals