Moriperan
Brand names,
Moriperan
Analogs
Moriperan
Brand Names Mixture
Moriperan
Chemical_Formula
C14H22ClN3O2
Moriperan
RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Moriperan
fda sheet
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msds (material safety sheet)
Moriperan
Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Moriperan
Molecular Weight
299.796 g/mol
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Melting Point
147.25 oC
Moriperan
H2O Solubility
200 mg/L
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State
Solid
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LogP
2.464
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Dosage Forms
Liquid; Syrup; Tablet
Moriperan
Indication
For the treatment of gastroesophageal reflux disease (GERD)
Moriperan
Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Moriperan
Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Moriperan
side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Moriperan
Patient Information
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Organisms Affected
Humans and other mammals