ranitin
Category
Useful info
ranitin Brand names, ranitin Analogs
ranitin Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
ranitin Chemical_Formula
C13H22N4O3S
ranitin RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
ranitin fda sheet
ranitin msds (material safety sheet)
ranitin Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
ranitin Molecular Weight
314.405 g/mol
ranitin Melting Point
69-70 oC
ranitin H2O Solubility
24.7 mg/mL
ranitin State
Solid
ranitin LogP
1.93
ranitin Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
ranitin Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
ranitin Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
ranitin Absorption
Approximately 50% bioavailability orally.
ranitin Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
ranitin Patient Information
APRD00254.html
ranitin Organisms Affected
Humans and other mammals
