Ranitidin Hexal
Category
Ranitidin Hexal Brand names, Ranitidin Hexal Analogs
Ranitidin Hexal Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidin Hexal Chemical_Formula
C13H22N4O3S
Ranitidin Hexal RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin Hexal fda sheet
Ranitidin Hexal msds (material safety sheet)
Ranitidin Hexal Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin Hexal Molecular Weight
314.405 g/mol
Ranitidin Hexal Melting Point
69-70 oC
Ranitidin Hexal H2O Solubility
24.7 mg/mL
Ranitidin Hexal State
Solid
Ranitidin Hexal LogP
1.93
Ranitidin Hexal Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin Hexal Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin Hexal Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin Hexal Absorption
Approximately 50% bioavailability orally.
Ranitidin Hexal Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin Hexal Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin Hexal Organisms Affected
Humans and other mammals