PharmacyCodes



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Melfax Brand names, Melfax Analogs

Melfax Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Melfax Chemical_Formula

C13H22N4O3S

Melfax RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Melfax fda sheet

Melfax FDA

Melfax msds (material safety sheet)

Melfax MSDS

Melfax Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Melfax Molecular Weight

314.405 g/mol

Melfax Melting Point

69-70 oC

Melfax H2O Solubility

24.7 mg/mL

Melfax State

Solid

Melfax LogP

1.93

Melfax Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Melfax Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Melfax Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Melfax Absorption

Approximately 50% bioavailability orally.

Melfax side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Melfax Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Melfax Organisms Affected

Humans and other mammals