Alquen
Category
Alquen Brand names, Alquen Analogs
Alquen Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Alquen Chemical_Formula
C13H22N4O3S
Alquen RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Alquen fda sheet
Alquen msds (material safety sheet)
Alquen Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Alquen Molecular Weight
314.405 g/mol
Alquen Melting Point
69-70 oC
Alquen H2O Solubility
24.7 mg/mL
Alquen State
Solid
Alquen LogP
1.93
Alquen Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Alquen Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Alquen Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Alquen Absorption
Approximately 50% bioavailability orally.
Alquen Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Alquen Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Alquen Organisms Affected
Humans and other mammals
