RAN

Category

RAN




Useful info

RAN Brand names, RAN Analogs

RAN Brand Names Mixture

  • No information avaliable

    • RAN Chemical_Formula

    C15H14ClN3O4S

    RAN RX_link

    http://www.rxlist.com/cgi/generic/cefaclor.htm

    RAN fda sheet

    RAN FDA

    RAN msds (material safety sheet)

    RAN MSDS

    RAN Synthesis Reference

    R. R. Chauvette, U.S. Pat. 3,925,372 (1975)

    RAN Molecular Weight

    367.808 g/mol

    RAN Melting Point

    327 oC

    RAN H2O Solubility

    8.6 mg/mL

    RAN State

    Solid

    RAN LogP

    0.517

    RAN Dosage Forms

    Capsule; Powder; Powder for solution; Powder for suspension; Suspension

    RAN Indication

    For the treatment of certain infections caused by bacteria such as pneumonia and ear, lung, skin, throat, and urinary tract infections.

    RAN Pharmacology

    Cefaclor is a second generation cephalosporin antibiotic with a spectrum resembling first-generation cephalosporins. In vitro tests demonstrate that the bactericidal action of the cephalosporins results from inhibition of cell-wall synthesis. Cefaclor has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Gram positive aerobes - Staphylococci (including coagulase-positive, coagulase-negative, and penicillinase-producing strains), Streptococcus pneumoniae, and Streptococcus pyogenes (group A ß-hemolytic streptococci). Gram-negative aerobes - Escherichia coli, Haemophilus influenzae (including ß-lactamase-producing ampicillin-resistant strains), Klebsiella sp, and Proteus mirabilis.

    RAN Absorption

    Well absorbed after oral administration, independent of food intake.

    RAN Toxicity

    Symptoms of overdose include diarrhea, nausea, stomach upset, and vomiting.

    RAN Patient Information

    Patients should be counseled that antibacterial drugs including Ceclor should only be used to treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Ceclor is prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by Ceclor or other antibacterial drugs in the future.

    RAN Organisms Affected

    Enteric bacteria and other eubacteria