Rani-BASF
Category
Rani-BASF Brand names, Rani-BASF Analogs
Rani-BASF Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Rani-BASF Chemical_Formula
C13H22N4O3S
Rani-BASF RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Rani-BASF fda sheet
Rani-BASF msds (material safety sheet)
Rani-BASF Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Rani-BASF Molecular Weight
314.405 g/mol
Rani-BASF Melting Point
69-70 oC
Rani-BASF H2O Solubility
24.7 mg/mL
Rani-BASF State
Solid
Rani-BASF LogP
1.93
Rani-BASF Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Rani-BASF Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Rani-BASF Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Rani-BASF Absorption
Approximately 50% bioavailability orally.
Rani-BASF Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Rani-BASF Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Rani-BASF Organisms Affected
Humans and other mammals
