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Rani-BASF Brand names, Rani-BASF Analogs

Rani-BASF Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Rani-BASF Chemical_Formula

C13H22N4O3S

Rani-BASF RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Rani-BASF fda sheet

Rani-BASF FDA

Rani-BASF msds (material safety sheet)

Rani-BASF MSDS

Rani-BASF Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Rani-BASF Molecular Weight

314.405 g/mol

Rani-BASF Melting Point

69-70 oC

Rani-BASF H2O Solubility

24.7 mg/mL

Rani-BASF State

Solid

Rani-BASF LogP

1.93

Rani-BASF Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Rani-BASF Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Rani-BASF Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Rani-BASF Absorption

Approximately 50% bioavailability orally.

Rani-BASF side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Rani-BASF Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Rani-BASF Organisms Affected

Humans and other mammals