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Logat Brand names, Logat Analogs

Logat Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Logat Chemical_Formula

C13H22N4O3S

Logat RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Logat fda sheet

Logat FDA

Logat msds (material safety sheet)

Logat MSDS

Logat Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Logat Molecular Weight

314.405 g/mol

Logat Melting Point

69-70 oC

Logat H2O Solubility

24.7 mg/mL

Logat State

Solid

Logat LogP

1.93

Logat Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Logat Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Logat Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Logat Absorption

Approximately 50% bioavailability orally.

Logat side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Logat Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Logat Organisms Affected

Humans and other mammals