Logat Brand names, Logat Analogs
Logat Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Logat fda sheet
Logat msds (material safety sheet)
Logat Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Logat Molecular Weight
Logat Melting Point
Logat H2O Solubility
Logat Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Approximately 50% bioavailability orally.
Logat side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Logat Patient Information
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Logat Organisms Affected
Humans and other mammals