Ranidin
Category
Ranidin Brand names, Ranidin Analogs
Ranidin Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranidin Chemical_Formula
C13H22N4O3S
Ranidin RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranidin fda sheet
Ranidin msds (material safety sheet)
Ranidin Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranidin Molecular Weight
314.405 g/mol
Ranidin Melting Point
69-70 oC
Ranidin H2O Solubility
24.7 mg/mL
Ranidin State
Solid
Ranidin LogP
1.93
Ranidin Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranidin Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranidin Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranidin Absorption
Approximately 50% bioavailability orally.
Ranidin Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranidin Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranidin Organisms Affected
Humans and other mammals
