Ranitidin Merck
Category
Ranitidin Merck Brand names, Ranitidin Merck Analogs
Ranitidin Merck Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidin Merck Chemical_Formula
C13H22N4O3S
Ranitidin Merck RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin Merck fda sheet
Ranitidin Merck msds (material safety sheet)
Ranitidin Merck Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin Merck Molecular Weight
314.405 g/mol
Ranitidin Merck Melting Point
69-70 oC
Ranitidin Merck H2O Solubility
24.7 mg/mL
Ranitidin Merck State
Solid
Ranitidin Merck LogP
1.93
Ranitidin Merck Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin Merck Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin Merck Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin Merck Absorption
Approximately 50% bioavailability orally.
Ranitidin Merck Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin Merck Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin Merck Organisms Affected
Humans and other mammals
