Pep-Rani
Category
Pep-Rani Brand names, Pep-Rani Analogs
Pep-Rani Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Pep-Rani Chemical_Formula
C13H22N4O3S
Pep-Rani RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Pep-Rani fda sheet
Pep-Rani msds (material safety sheet)
Pep-Rani Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Pep-Rani Molecular Weight
314.405 g/mol
Pep-Rani Melting Point
69-70 oC
Pep-Rani H2O Solubility
24.7 mg/mL
Pep-Rani State
Solid
Pep-Rani LogP
1.93
Pep-Rani Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Pep-Rani Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Pep-Rani Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Pep-Rani Absorption
Approximately 50% bioavailability orally.
Pep-Rani Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Pep-Rani Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Pep-Rani Organisms Affected
Humans and other mammals
