Raniogas
Category
Raniogas Brand names, Raniogas Analogs
Raniogas Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Raniogas Chemical_Formula
C13H22N4O3S
Raniogas RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Raniogas fda sheet
Raniogas msds (material safety sheet)
Raniogas Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Raniogas Molecular Weight
314.405 g/mol
Raniogas Melting Point
69-70 oC
Raniogas H2O Solubility
24.7 mg/mL
Raniogas State
Solid
Raniogas LogP
1.93
Raniogas Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Raniogas Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Raniogas Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Raniogas Absorption
Approximately 50% bioavailability orally.
Raniogas Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Raniogas Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Raniogas Organisms Affected
Humans and other mammals
