PharmacyCodes



Zantic en es it fr

Zantic Brand names, Zantic Analogs

Zantic Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Zantic Chemical_Formula

C13H22N4O3S

Zantic RX_link

http://www.rxlist.com/cgi/generic2/ranitbc.htm

Zantic fda sheet

Zantic FDA

Zantic msds (material safety sheet)

Zantic MSDS

Zantic Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Zantic Molecular Weight

314.405 g/mol

Zantic Melting Point

69-70 oC

Zantic H2O Solubility

24.7 mg/mL

Zantic State

Solid

Zantic LogP

1.93

Zantic Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Zantic Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Zantic Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Zantic Absorption

Approximately 50% bioavailability orally.

Zantic side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Zantic Patient Information

PATIENT INFORMATION

Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Zantic Organisms Affected

Humans and other mammals