Apo-Ranitidin
Category
Apo-Ranitidin Brand names, Apo-Ranitidin Analogs
Apo-Ranitidin Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Apo-Ranitidin Chemical_Formula
C13H22N4O3S
Apo-Ranitidin RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Apo-Ranitidin fda sheet
Apo-Ranitidin msds (material safety sheet)
Apo-Ranitidin Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Apo-Ranitidin Molecular Weight
314.405 g/mol
Apo-Ranitidin Melting Point
69-70 oC
Apo-Ranitidin H2O Solubility
24.7 mg/mL
Apo-Ranitidin State
Solid
Apo-Ranitidin LogP
1.93
Apo-Ranitidin Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Apo-Ranitidin Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Apo-Ranitidin Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Apo-Ranitidin Absorption
Approximately 50% bioavailability orally.
Apo-Ranitidin Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Apo-Ranitidin Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Apo-Ranitidin Organisms Affected
Humans and other mammals
