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Lake Brand names, Lake Analogs

Lake Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Lake Chemical_Formula


Lake RX_link

Lake fda sheet

Lake FDA

Lake msds (material safety sheet)


Lake Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Lake Molecular Weight

314.405 g/mol

Lake Melting Point

69-70 oC

Lake H2O Solubility

24.7 mg/mL

Lake State


Lake LogP


Lake Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Lake Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Lake Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Lake Absorption

Approximately 50% bioavailability orally.

Lake side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Lake Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Lake Organisms Affected

Humans and other mammals