Ranitidin NM
Category
Ranitidin NM Brand names, Ranitidin NM Analogs
Ranitidin NM Brand Names Mixture
- Tritec (ranitidine bismuth citrate salt)
Ranitidin NM Chemical_Formula
C13H22N4O3S
Ranitidin NM RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin NM fda sheet
Ranitidin NM msds (material safety sheet)
Ranitidin NM Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin NM Molecular Weight
314.405 g/mol
Ranitidin NM Melting Point
69-70 oC
Ranitidin NM H2O Solubility
24.7 mg/mL
Ranitidin NM State
Solid
Ranitidin NM LogP
1.93
Ranitidin NM Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin NM Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin NM Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin NM Absorption
Approximately 50% bioavailability orally.
Ranitidin NM side effects and Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin NM Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin NM Organisms Affected
Humans and other mammals
