Ran_Lich
Category
Ran_Lich Brand names, Ran_Lich Analogs
Ran_Lich Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ran_Lich Chemical_Formula
C13H22N4O3S
Ran_Lich RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ran_Lich fda sheet
Ran_Lich msds (material safety sheet)
Ran_Lich Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ran_Lich Molecular Weight
314.405 g/mol
Ran_Lich Melting Point
69-70 oC
Ran_Lich H2O Solubility
24.7 mg/mL
Ran_Lich State
Solid
Ran_Lich LogP
1.93
Ran_Lich Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ran_Lich Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ran_Lich Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ran_Lich Absorption
Approximately 50% bioavailability orally.
Ran_Lich Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ran_Lich Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ran_Lich Organisms Affected
Humans and other mammals
