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Label Brand names, Label Analogs

Label Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Label Chemical_Formula


Label RX_link

Label fda sheet

Label FDA

Label msds (material safety sheet)

Label MSDS

Label Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Label Molecular Weight

314.405 g/mol

Label Melting Point

69-70 oC

Label H2O Solubility

24.7 mg/mL

Label State


Label LogP


Label Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Label Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Label Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Label Absorption

Approximately 50% bioavailability orally.

Label side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Label Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Label Organisms Affected

Humans and other mammals