Ranitidina_predilu_Grif
Category
Ranitidina_predilu_Grif Brand names, Ranitidina_predilu_Grif Analogs
Ranitidina_predilu_Grif Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranitidina_predilu_Grif Chemical_Formula
C13H22N4O3S
Ranitidina_predilu_Grif RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidina_predilu_Grif fda sheet
Ranitidina_predilu_Grif msds (material safety sheet)
Ranitidina_predilu_Grif Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidina_predilu_Grif Molecular Weight
314.405 g/mol
Ranitidina_predilu_Grif Melting Point
69-70 oC
Ranitidina_predilu_Grif H2O Solubility
24.7 mg/mL
Ranitidina_predilu_Grif State
Solid
Ranitidina_predilu_Grif LogP
1.93
Ranitidina_predilu_Grif Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidina_predilu_Grif Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidina_predilu_Grif Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidina_predilu_Grif Absorption
Approximately 50% bioavailability orally.
Ranitidina_predilu_Grif Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidina_predilu_Grif Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidina_predilu_Grif Organisms Affected
Humans and other mammals