Raniben
Category
Raniben Brand names, Raniben Analogs
Raniben Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Raniben Chemical_Formula
C13H22N4O3S
Raniben RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Raniben fda sheet
Raniben msds (material safety sheet)
Raniben Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Raniben Molecular Weight
314.405 g/mol
Raniben Melting Point
69-70 oC
Raniben H2O Solubility
24.7 mg/mL
Raniben State
Solid
Raniben LogP
1.93
Raniben Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Raniben Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Raniben Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Raniben Absorption
Approximately 50% bioavailability orally.
Raniben Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Raniben Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Raniben Organisms Affected
Humans and other mammals
