Ranitidin_Atid
Category
Ranitidin_Atid Brand names, Ranitidin_Atid Analogs
Ranitidin_Atid Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranitidin_Atid Chemical_Formula
C13H22N4O3S
Ranitidin_Atid RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin_Atid fda sheet
Ranitidin_Atid msds (material safety sheet)
Ranitidin_Atid Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin_Atid Molecular Weight
314.405 g/mol
Ranitidin_Atid Melting Point
69-70 oC
Ranitidin_Atid H2O Solubility
24.7 mg/mL
Ranitidin_Atid State
Solid
Ranitidin_Atid LogP
1.93
Ranitidin_Atid Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin_Atid Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin_Atid Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin_Atid Absorption
Approximately 50% bioavailability orally.
Ranitidin_Atid Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin_Atid Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin_Atid Organisms Affected
Humans and other mammals
