Mideran
Category
Mideran Brand names, Mideran Analogs
Mideran Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Mideran Chemical_Formula
C13H22N4O3S
Mideran RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Mideran fda sheet
Mideran msds (material safety sheet)
Mideran Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Mideran Molecular Weight
314.405 g/mol
Mideran Melting Point
69-70 oC
Mideran H2O Solubility
24.7 mg/mL
Mideran State
Solid
Mideran LogP
1.93
Mideran Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Mideran Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Mideran Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Mideran Absorption
Approximately 50% bioavailability orally.
Mideran Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Mideran Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Mideran Organisms Affected
Humans and other mammals
