Ranigasan
Category
Ranigasan Brand names, Ranigasan Analogs
Ranigasan Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranigasan Chemical_Formula
C13H22N4O3S
Ranigasan RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranigasan fda sheet
Ranigasan msds (material safety sheet)
Ranigasan Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranigasan Molecular Weight
314.405 g/mol
Ranigasan Melting Point
69-70 oC
Ranigasan H2O Solubility
24.7 mg/mL
Ranigasan State
Solid
Ranigasan LogP
1.93
Ranigasan Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranigasan Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranigasan Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranigasan Absorption
Approximately 50% bioavailability orally.
Ranigasan Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranigasan Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranigasan Organisms Affected
Humans and other mammals
