Ranidura
Category
Ranidura Brand names, Ranidura Analogs
Ranidura Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranidura Chemical_Formula
C13H22N4O3S
Ranidura RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranidura fda sheet
Ranidura msds (material safety sheet)
Ranidura Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranidura Molecular Weight
314.405 g/mol
Ranidura Melting Point
69-70 oC
Ranidura H2O Solubility
24.7 mg/mL
Ranidura State
Solid
Ranidura LogP
1.93
Ranidura Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranidura Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranidura Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranidura Absorption
Approximately 50% bioavailability orally.
Ranidura Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranidura Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranidura Organisms Affected
Humans and other mammals
