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Esofex Brand names, Esofex Analogs

Esofex Brand Names Mixture

  • Tritec (ranitidine bismuth citrate salt)

Esofex Chemical_Formula


Esofex RX_link

Esofex fda sheet

Esofex FDA

Esofex msds (material safety sheet)

Esofex MSDS

Esofex Synthesis Reference

B. J. Price et al., U.S. Pat. 4,128,658 (1978)

Esofex Molecular Weight

314.405 g/mol

Esofex Melting Point

69-70 oC

Esofex H2O Solubility

24.7 mg/mL

Esofex State


Esofex LogP


Esofex Dosage Forms

Capsule; Liquid; Solution; Tablet; Syrup

Esofex Indication

Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).

Esofex Pharmacology

Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.

Esofex Absorption

Approximately 50% bioavailability orally.

Esofex side effects and Toxicity

LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.

Esofex Patient Information


Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.

Esofex Organisms Affected

Humans and other mammals