Ranitidin_Duncan
Category
Ranitidin_Duncan Brand names, Ranitidin_Duncan Analogs
Ranitidin_Duncan Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranitidin_Duncan Chemical_Formula
C13H22N4O3S
Ranitidin_Duncan RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranitidin_Duncan fda sheet
Ranitidin_Duncan msds (material safety sheet)
Ranitidin_Duncan Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranitidin_Duncan Molecular Weight
314.405 g/mol
Ranitidin_Duncan Melting Point
69-70 oC
Ranitidin_Duncan H2O Solubility
24.7 mg/mL
Ranitidin_Duncan State
Solid
Ranitidin_Duncan LogP
1.93
Ranitidin_Duncan Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranitidin_Duncan Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranitidin_Duncan Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranitidin_Duncan Absorption
Approximately 50% bioavailability orally.
Ranitidin_Duncan Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranitidin_Duncan Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranitidin_Duncan Organisms Affected
Humans and other mammals
