Ranimerck
Category
Ranimerck Brand names, Ranimerck Analogs
Ranimerck Brand Names Mixture
Tritec (ranitidine bismuth citrate salt)
Ranimerck Chemical_Formula
C13H22N4O3S
Ranimerck RX_link
http://www.rxlist.com/cgi/generic2/ranitbc.htm
Ranimerck fda sheet
Ranimerck msds (material safety sheet)
Ranimerck Synthesis Reference
B. J. Price et al., U.S. Pat. 4,128,658 (1978)
Ranimerck Molecular Weight
314.405 g/mol
Ranimerck Melting Point
69-70 oC
Ranimerck H2O Solubility
24.7 mg/mL
Ranimerck State
Solid
Ranimerck LogP
1.93
Ranimerck Dosage Forms
Capsule; Liquid; Solution; Tablet; Syrup
Ranimerck Indication
Used in the treatment of peptic ulcer disease (PUD), dyspepsia, stress ulcer prophylaxis, and gastroesophageal reflux disease (GERD).
Ranimerck Pharmacology
Ranitidine is a histamine H2-receptor antagonist similar to cimetidine and famotidine. An H2-receptor antagonist, often shortened to H2 antagonist, is a drug used to block the action of histamine on parietal cells in the stomach, decreasing acid production by these cells. These drugs are used in the treatment of dyspepsia, however their use has waned since the advent of the more effective proton pump inhibitors. Like the H1-antihistamines, the H2 antagonists are inverse agonists rather than true receptor antagonists.
Ranimerck Absorption
Approximately 50% bioavailability orally.
Ranimerck Toxicity
LD50=77mg/kg (orally in mice). Symptoms of overdose include muscular tremors, vomiting, and rapid respiration.
Ranimerck Patient Information
PATIENT INFORMATION
Phenylketonurics: ZANTAC 25 EFFERdose Tablets contain phenylalanine 2.81 mg per 25 mg of ranitidine. ZANTAC 150 EFFERdose Tablets
contain phenylalanine 16.84 mg per 150 mg of ranitidine. ZANTAC EFFERdose Tablets should not be chewed, swallowed whole, or dissolved
on the tongue.
Ranimerck Organisms Affected
Humans and other mammals
