Repromap
Brand names,
Repromap
Analogs
Repromap
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Repromap
Chemical_Formula
C22H32O3
Repromap
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Repromap
fda sheet
Repromap
msds (material safety sheet)
Repromap
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Repromap
Molecular Weight
344.488 g/mol
Repromap
Melting Point
220 - 223.5 oC
Repromap
H2O Solubility
22.2mg/L
Repromap
State
Solid
Repromap
LogP
3.606
Repromap
Dosage Forms
Tablets; Depo injection
Repromap
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Repromap
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Repromap
Absorption
Rapidly absorbed from GI tract
Repromap
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Repromap
Patient Information
Repromap
Organisms Affected
Humans and other mammals