Medroxyprogesteron acetate
Brand names,
Medroxyprogesteron acetate
Analogs
Medroxyprogesteron acetate
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesteron acetate
Chemical_Formula
C22H32O3
Medroxyprogesteron acetate
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesteron acetate
fda sheet
Medroxyprogesteron acetate
msds (material safety sheet)
Medroxyprogesteron acetate
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesteron acetate
Molecular Weight
344.488 g/mol
Medroxyprogesteron acetate
Melting Point
220 - 223.5 oC
Medroxyprogesteron acetate
H2O Solubility
22.2mg/L
Medroxyprogesteron acetate
State
Solid
Medroxyprogesteron acetate
LogP
3.606
Medroxyprogesteron acetate
Dosage Forms
Tablets; Depo injection
Medroxyprogesteron acetate
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesteron acetate
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesteron acetate
Absorption
Rapidly absorbed from GI tract
Medroxyprogesteron acetate
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesteron acetate
Patient Information
Medroxyprogesteron acetate
Organisms Affected
Humans and other mammals