Indivina
Brand names,
Indivina
Analogs
Indivina
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Indivina
Chemical_Formula
C22H32O3
Indivina
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Indivina
fda sheet
Indivina
msds (material safety sheet)
Indivina
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Indivina
Molecular Weight
344.488 g/mol
Indivina
Melting Point
220 - 223.5 oC
Indivina
H2O Solubility
22.2mg/L
Indivina
State
Solid
Indivina
LogP
3.606
Indivina
Dosage Forms
Tablets; Depo injection
Indivina
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Indivina
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Indivina
Absorption
Rapidly absorbed from GI tract
Indivina
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Indivina
Patient Information
Indivina
Organisms Affected
Humans and other mammals