Perlutex
Brand names,
Perlutex
Analogs
Perlutex
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Perlutex
Chemical_Formula
C22H32O3
Perlutex
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Perlutex
fda sheet
Perlutex
msds (material safety sheet)
Perlutex
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Perlutex
Molecular Weight
344.488 g/mol
Perlutex
Melting Point
220 - 223.5 oC
Perlutex
H2O Solubility
22.2mg/L
Perlutex
State
Solid
Perlutex
LogP
3.606
Perlutex
Dosage Forms
Tablets; Depo injection
Perlutex
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Perlutex
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Perlutex
Absorption
Rapidly absorbed from GI tract
Perlutex
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Perlutex
Patient Information
Perlutex
Organisms Affected
Humans and other mammals