DMPA
Brand names,
DMPA
Analogs
DMPA
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
DMPA
Chemical_Formula
C22H32O3
DMPA
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
DMPA
fda sheet
DMPA
msds (material safety sheet)
DMPA
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
DMPA
Molecular Weight
344.488 g/mol
DMPA
Melting Point
220 - 223.5 oC
DMPA
H2O Solubility
22.2mg/L
DMPA
State
Solid
DMPA
LogP
3.606
DMPA
Dosage Forms
Tablets; Depo injection
DMPA
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
DMPA
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
DMPA
Absorption
Rapidly absorbed from GI tract
DMPA
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
DMPA
Patient Information
DMPA
Organisms Affected
Humans and other mammals