Crinone
Brand names,
Crinone
Analogs
Crinone
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Crinone
Chemical_Formula
C22H32O3
Crinone
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Crinone
fda sheet
Crinone
msds (material safety sheet)
Crinone
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Crinone
Molecular Weight
344.488 g/mol
Crinone
Melting Point
220 - 223.5 oC
Crinone
H2O Solubility
22.2mg/L
Crinone
State
Solid
Crinone
LogP
3.606
Crinone
Dosage Forms
Tablets; Depo injection
Crinone
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Crinone
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Crinone
Absorption
Rapidly absorbed from GI tract
Crinone
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Crinone
Patient Information
Crinone
Organisms Affected
Humans and other mammals