Medroxyprogesterone acetate
Brand names,
Medroxyprogesterone acetate
Analogs
Medroxyprogesterone acetate
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medroxyprogesterone acetate
Chemical_Formula
C22H32O3
Medroxyprogesterone acetate
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroxyprogesterone acetate
fda sheet
Medroxyprogesterone acetate
msds (material safety sheet)
Medroxyprogesterone acetate
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroxyprogesterone acetate
Molecular Weight
344.488 g/mol
Medroxyprogesterone acetate
Melting Point
220 - 223.5 oC
Medroxyprogesterone acetate
H2O Solubility
22.2mg/L
Medroxyprogesterone acetate
State
Solid
Medroxyprogesterone acetate
LogP
3.606
Medroxyprogesterone acetate
Dosage Forms
Tablets; Depo injection
Medroxyprogesterone acetate
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroxyprogesterone acetate
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroxyprogesterone acetate
Absorption
Rapidly absorbed from GI tract
Medroxyprogesterone acetate
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroxyprogesterone acetate
Patient Information
Medroxyprogesterone acetate
Organisms Affected
Humans and other mammals