Perlutex Leo
Brand names,
Perlutex Leo
Analogs
Perlutex Leo
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Perlutex Leo
Chemical_Formula
C22H32O3
Perlutex Leo
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Perlutex Leo
fda sheet
Perlutex Leo
msds (material safety sheet)
Perlutex Leo
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Perlutex Leo
Molecular Weight
344.488 g/mol
Perlutex Leo
Melting Point
220 - 223.5 oC
Perlutex Leo
H2O Solubility
22.2mg/L
Perlutex Leo
State
Solid
Perlutex Leo
LogP
3.606
Perlutex Leo
Dosage Forms
Tablets; Depo injection
Perlutex Leo
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Perlutex Leo
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Perlutex Leo
Absorption
Rapidly absorbed from GI tract
Perlutex Leo
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Perlutex Leo
Patient Information
Perlutex Leo
Organisms Affected
Humans and other mammals