Medroprogesterone Acetate
Brand names,
Medroprogesterone Acetate
Analogs
Medroprogesterone Acetate
Brand Names Mixture
- Lunelle (Medroxyprogesterone + Estradiol)
Medroprogesterone Acetate
Chemical_Formula
C22H32O3
Medroprogesterone Acetate
RX_link
http://www.rxlist.com/cgi/generic/medrox.htm
Medroprogesterone Acetate
fda sheet
Medroprogesterone Acetate
msds (material safety sheet)
Medroprogesterone Acetate
Synthesis Reference
P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)
Medroprogesterone Acetate
Molecular Weight
344.488 g/mol
Medroprogesterone Acetate
Melting Point
220 - 223.5 oC
Medroprogesterone Acetate
H2O Solubility
22.2mg/L
Medroprogesterone Acetate
State
Solid
Medroprogesterone Acetate
LogP
3.606
Medroprogesterone Acetate
Dosage Forms
Tablets; Depo injection
Medroprogesterone Acetate
Indication
Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.
Medroprogesterone Acetate
Pharmacology
Medroxyprogesterone is a synthetic progestin more potent than progesterone.
Medroprogesterone Acetate
Absorption
Rapidly absorbed from GI tract
Medroprogesterone Acetate
side effects and Toxicity
Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.
Medroprogesterone Acetate
Patient Information
Medroprogesterone Acetate
Organisms Affected
Humans and other mammals