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MPA Brand names, MPA Analogs

MPA Brand Names Mixture

  • Lunelle (Medroxyprogesterone + Estradiol)

MPA Chemical_Formula

C22H32O3

MPA RX_link

http://www.rxlist.com/cgi/generic/medrox.htm

MPA fda sheet

MPA FDA

MPA msds (material safety sheet)

MPA Synthesis Reference

P. Ruggieri, C. Ferrari, U.S. Pat. 3,043,832 (1962)

MPA Molecular Weight

344.488 g/mol

MPA Melting Point

220 - 223.5 oC

MPA H2O Solubility

22.2mg/L

MPA State

Solid

MPA LogP

3.606

MPA Dosage Forms

Tablets; Depo injection

MPA Indication

Used as a contraceptive and to treat amenorrhea, abnormal uterine bleeding, endometriosis, endometrial and renal cell carcinomas, and pulmonary disorders such as chronic obstructive pulmonary disease (COPD), Pickwickian syndrome, and other hypercapnic pulmonary conditions.

MPA Pharmacology

Medroxyprogesterone is a synthetic progestin more potent than progesterone.

MPA Absorption

Rapidly absorbed from GI tract

MPA side effects and Toxicity

Side effects include loss of bone mineral density, BMD changes in adult women, bleeding irregularities, cancer risks, and thromboembolic disorders.

MPA Patient Information

MPA Organisms Affected

Humans and other mammals